Meet the 2025 Game Changers
The eight game-changer sessions at the American Physiology Summit feature some of the biggest topics impacting life and health today. Top scientists from around the world will come together to present on these vital issues.
Diabetes | Xenotransplantation | Bioelectric Medicine | Longevity | Maternal Behaviors | Sleep and Health | Inflammation and Immunology | Breathwork
The Risks and Rewards of GLP-1 Agonists Beyond Diabetes
This session will discuss how GLP-1 agonists—originally designed to combat diabetes and obesity—are now being investigated for their potential to improve cardiovascular function and reduce opioid addiction. Rick Samson, PhD, DSc, FAPS, and Ann Schreihofer, PhD, FAPS, are the session chairs.
Speakers
Karolina Skibicka, PhD
The Pennsylvania State University
Kieren Mather, MD
Eli Lilly and Company
Breakthroughs in Xenotransplantation
This session will explore recent advancements and address significant challenges in xenotransplantation—the use of organs from non-human animals, primarily pigs—as a potential solution to the organ shortage crisis. Farah Sheikh, PhD, is the session chair.
Speakers
Kelly Anne Hyndman, PhD
University of Alabama at Birmingham
Muhammad Mohiuddin, MD/MBBS, DSc (Hon), FAST
University of Maryland
Bioelectric Medicine: Neural Modulation of Central and Peripheral Function
This session will highlight novel and state-of-the art research that uses electroceutical techniques to modulate central and peripheral organ function and behavior, in health and disease, at the neuronal level. Gordon S. Mitchell, PhD, FAPS, and Irving H. Zucker, PhD, FAPS, are the session chairs.
Speakers
Michael Kilgard, PhD
University of Texas at Dallas
Marco Capogrosso, PhD
Texas Biomedical Device Center
Unlocking Longevity through Advances in Nutrition, Exercise and Epigenetics
This session will highlight new and emerging areas in nutrition, exercise and epigenetics and their influence on the physiology of longevity. We’ll explore how this translates into potential healthspan-extending treatments. Benjamin Miller, PhD, FAPS, and Jennifer Steiner, PhD, are the session chairs.
Speakers
Luigi Ferrucci, MD, PhD
National Institute on Aging
Rafa DeCabo, PhD
National Institute on Aging
Rozalyn Anderson, PhD
University of Wisconsin
Unraveling the Link between Maternal Behaviors and Offspring Disease
This session will present new findings from basic and clinical research that show how maternal behaviors may affect health outcomes in offspring. Kathryn Hamilton, PhD, and Evangeline Deer, PhD, are the session chairs.
Speakers
Kristin Stanford, PhD
The Ohio State University
Tracy Baker, PhD
University of Wisconsin-Madison
Circadian Rhythm's Impact on Sleep and Health
This session will discuss how sleep and circadian rhythms interact to influence physiological health, homeostasis and human disease. Josie Broussard, PhD, and Jason Carter, PhD, FAPS, are the session chairs.
Speakers
Ketema Paul, PhD
UCLA
Kristen Knutson, PhD
Northwestern University Feinberg School of Medicine
Kenneth Wright, PhD
University of Colorado Boulder
Discoveries at the Intersection of Inflammation and Immunology
This session will explore the intricacies of inflammation and immunology. Talks will delve into the cutting-edge intersections of ecoimmunology, the microbiome and immune cell membrane physiology. Denise Cornelius, PhD, and Elaine Lee, PhD, are the session chairs.
Speakers
Lynn Martin, PhD
University of South Florida
Stefan Feske, MD
New York University School of Medicine
R. Balfour Sartor, MD
University of North Carolina
The Science Behind Breathwork and Why it Matters
This session will explore the mechanisms through which controlled breathing (breathwork) reduces anxiety and inflammation. We'll explore how intermittent exposure to low oxygen environments promotes plasticity. Gordon S. Mitchell, PhD, FAPS is the session chair.
Speakers
Alicia Meuret, PhD
Southern Methodist University
Jack Feldman, PhD
David Geffen School of Medicine at UCLA

Harvard Medical School
Summit Menu
- Abstracts
- Advocate for Women's Health Research Funding
- Awards
- Award Lectures
- Dates and Deadlines
- Game Changers
- Industry Partner Workshops
- Keynote Speaker—James Rothman, PhD
- Keynote Speaker—George Brooks, PhD, FAPS
- Keynote Speaker—Holly Ingraham, PhD
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